As explained on our homepage as well as our resources page, the main goal of the CNL is to explain how microanatomical structures generate macroanatomical functions contributing to measurable behaviors. Achieving this ultimate goal requires a multi-modal approach, international collaborations, and data sharing.

Specifically, the CNL implements both non-invasive methods [e.g., functional magnetic resonance imaging (fMRI), diffusion MRI (dMRI), morphological analyses of cortical folding, and quantitative T1 measurements in children, adults, and patients], as well as more invasive, translational methods in living brains (e.g., electrocorticography and electrical brain stimulation), and high-resolution methods in post- mortem brains (e.g., cytoarchitectonics). This combinatorial approach reflects the CNL research philosophy, which is that investigations of functional architecture should be guided by a deep understanding of structural-functional relationships. To that end, we apply a bottom up, neuroanatomist’s approach to the study of psychology, and specifically, human perception. Such an approach leverages many types of neural measurements at the finest scale possible in humans, in conjunction with behavioral experiments and case studies to best understand how features of the brain – from cells to systems – support and contribute to human perception. Here is a snapshot of some current CNL projects:

High-resolution fMRI of human cortical systems

The microarchitecture of functional regions in human cortex

The anatomical connectivity of cortical systems

Neural development of high-level visual processing

The effect of stimulus repetition on neural responses and neural representations

Translational applications in patients

Comparative anatomical and functional measurements across species

Data sharing and atlasing

History of neuroscience